가천대학교 약학대학 천연물 기반 화학생물학 연구실
Laboratory of Natural Products Based Chemical Biology
We are targeting structurally and biologically novel natural products from microbes based on
analysis of chemical profiles, cheminformatics and deep-molecular networking system.
Furthermore, we are investigating symbiotic interaction between hosts and microbes chemically,
providing deep-insights into understanding role of microbes and new strategies for drug development.
NEWS
2026. 10. 10
Good News!! Our PI was awarded "Korea Ginseng Research Grant", leading a bio-transformation of velvet antler via ginseng-derived microbiome!
Our lab will be supported by research grant for "Discovery of Novel Ginseng-Derived Microbiome Biotransformants and Their Metabolic-Immune Modulatory Effects for Gut Health". Let's dive into the Korean ginseng world!!
2026. 08. 31
Great News!! Jungro Lee in Ph.D course was awarded the "Research Grant for Doctoral Candidates", leading an unnatural-natural product discovery for novel antibiotics for 3 years!!
Our Ph.D student Jungro Lee has been selected for the "Research Grant for Doctoral Candidates", a competitive national research funding program designed to support outstanding doctoral researchers with strong academic potential and innovative research capabilities. This prestigious fellowship provides independent research support to promising young scientists, recognizing both the scientific excellence of the proposed research and the researcher’s potential for future leadership. Congrats!
2026. 06. 04
Congratulations!! Our lab paper has been published in Natural Product Reports (IF: 12.5, JCR 2.1%)!!
Our research titled "Natural products with atypical atoms: unveiling structures, biosynthetic pathways, and bioactivities" is now available in Natural Product Reports, which is one of the highest ranked journals in Naturl Products field (JCR 2.1%)
2026. 04. 11
Congratulations! Hyojune Park in Ph.D course was awarded the "Excellent Poster Presentation Award" from the 1st A3 Foresight Symposium on Synthetic Biology-Driven Natural Product Research!
Hyojune's poster 'Subtilosin B: A New Derivative of Subtilosin A Isolated From Barnacle-Associated Bacillus subtilis sp. HJ9' was selected as the excellent poster presentation award! Congrats!
2026. 03. 13
Amazing News!! Our PI was awarded "Long-term Basic Research Support Program in One Field", leading a cutting-edge biopharmaceutical project for 10 years (2026 - 2036)! Awesome!!
'Long-term Basic Research Support Program in One Field' is designed to support outstanding young researchers in consistently conducting challenging and innovative basic research in a single field over an extended period, thereby enabling them to produce world-class research outcomes. A total of 30 researchers were selected across all fields of science and technology. 기초연구사업’ 선정
2025. 10. 24
Congratulations! Juwan Son in Ph.D course was awarded the "Outstanding Oral Presentation Award" from the 2025 Fall International Convention of the Pharmaceutical Society of Korea!!
Juwan's poster "Mohangic acid H and mohangiol: new p-aminoacetophenone derivatives from a mudflat-derived Streptomyces sp." was selected as the outstanding oral presentation! Congrats!.
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2025. 10. 24
Congratulations! Sang Heon Jung in Ph.D course was awarded the "Excellent Poster Presentation Award" from the 2025 Fall International Convention of the Pharmaceutical Society of Korea!!
Sang Heon's poster "Sakomycins A-D, New Heptaenoic Acids from Streptomyces Strain Derived from Volcanic Islands" was selected as the excellent poster presentation! Congrats!.
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2025. 10. 17
Congratulations! Ran Hui Kim in Ph.D course was awarded the "Excellent Poster Presentation Award" from the 2025 33rd Annual Meeting of the Korean Society of Applied Pharmacology!!
Ran Hui's poster "Okgyeamides A-C, New Cyclic RiPPs Produced by Cave-Derived Streptomyces sp." was selected as the excellent poster presentation! Congrats!.
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2025. 7. 08
Good News! Our lab has joined A3 Foresight Program for global synthetic biology collaboration!!
A3 foresight program titled "A3 Synthetic Biology-Driven Natural Product Research and Hub Acceleration" encourages Korea-Japan-China global collaboration for synthetic biology research and fosters the next generation of synthetic biologists.
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2025. 6. 27
Congratulations! Jungro Lee in Ph.D course was awarded the "Excellent Poster Presentation Award" from the 2025 52nd Annual Meeting & International Symposium of KMB!!
Jungro's poster "Igidamycins A-C, Unprecedented Sugar-Bearing Anthracycline Glycosides from a Marine Actinomycete, Streptomyces sp., was selected as the excellent poster presentation! Congrats!
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2025. 2. 17
Great News!! Revident LC-Q-TOF, the latest ultra-high resolution mass spectrometry model of Agilent, is now available! Let's start advanced metabolomics research!
Next generation high resolution quadrupole time of flight mass spectrometer is the most powerful machine for metabolomics, chemical profiling, and drug discovery. We are now ready to start bioinformatics. Congrats!
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2024. 11. 15
Anaerobic chamber is now available! It is time to investigate the Human Microbiome World!!
Human gut microbes can only grow under anaerobic conditions. Our lab set up the anaerobic chamber, including a light-shielding incubator and a large space for the experiment. Welcome to the Human Mircrobiome World!
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2024. 10. 11
Our PI was awarded "Young Investigator Academic Award" from the Korean Society of Applied Pharmacology! Congratulations!
In the the 32nd Annual Meeting and Symposium of the Korean Society of Applied Pharmacology, our PI was awarded as an Emerging Scholar!
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2024. 06. 17
Great News!! Our PI was awarded "Young Investigator Infrastructure Support", installing Next-Generation Ultra High-Resolution Mass Spectrometry. Congratulations!
Our lab will be supported reserach grant for "Advanced Convergent Bio-Intelligent Analytical System Based Quadrupole Time of Flight Mass Spectrometer". Let's explore multi-omics world!
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2024. 05. 31
Our lab was awarded "Laboratory Environmental Improvement Support Project", separating research and experiment spaces, respectively. Great News!
Our lab was supported grant for laboratory space separation to improve environment of laboratory and student's wellness. Congratulations!!
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2024. 02. 16
Our PI was awarded "17th Best Research Investigator in Pharmacy" from Handok Jeseok Foundation! Congratulations!
Our lab will be supported reserach grant for "Discovery of bioactive molecules and its biosynthesis derived from human gut bacterium Collinsella aerofacience". Great news!!
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2023. 09. 12
Gilson HPLC is now available! Let's dig in Natural Products!
High-Performance Liquid Chromatography is main facility for isolation and purifiaction of microbial natural products. Our lab is now installed Gilson HPLC. Iit is time to dive into the natural product's world!!
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2023. 04. 26
Big News!! Our lab was awarded "Bio-Medical Technology Development Project", which is a National Project for Microbiome. Conglatulations!!
National Research Foundation of Korea will support our team research titled "Development of novel microbiome-derived materials and production platform for metabolic disease control". Our lab will perform the analysis of novel metabolites from gut microbes and establishment of molecular database platform!!
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2023. 03. 23
Congratulations!! Our lab paper has been published in JACS (IF: 16.383)!!
Our research titled "Collinsella aerofaciens Produces a pH-Responsive Lipid Immunogen" is now available in Journal of the American Chemical Society, which is one of the highest ranked journals in chemistry field (JCR 4.24%).
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2023. 02. 24
Congratulations!! Our lab was awarded "Excellent Young Research Program" grant funding!
National Research Foundation of Korea will support our research titled "Discovery of new bioactive natural products regulating intestinal immune response from human gut bacterium Bifidobacterium breve".
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2023. 01. 19
High Performence Liquid Chromatography-Mass Spectrometry (HPLC-MS) system is now available!!
Agilent 1260 infinity ll LC-MS system eqquiped with fraction collector has been set up in our laboratory! Our lab is now possible to analyze and purify various type of novel natural products and gut metabolites!
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2022. 09. 14
Congratulations!! Our lab paper has been highlighted in Cell Host & Microbe (IF: 31.316)!!
Our Nature paper "Akkermansia muciniphila phospholipid induces homeostatic immune responses" has been highlighted in Cell Host & Microbe, which is 1st ranked journal in Parasitology field (1/39, JCR 1. 28%).
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2022. 08. 17
Congratulations!! Our lab joined the Brain Korea 21 Four team of college of pharmacy in Gachon University!!
Brain Korea 21 Four project is launched for manpower training of master and PhD courses. Our lab members will be supported by Brain Korea 21 Four funding from 2023!
2022. 07. 27
Congratulations!! Our lab paper has been published in Nature (IF: 69.504)!!
Our research titled "Akkermansia muciniphila phospholipid induces homeostatic immune responses" is now available in online. Our paper has been highlighted in medical news below!
- Bacterial bullseye | ScienMag
- Bacterial Bullseye | Sciencenewsnet.in
- Alle origini del diabete: l’occhio di bue batterico | Il mio diabete
- Researchers unravel how one gut bacterium influences immunity | The Medical News
- The Impact of One Gut Microbe on Human Immunity is Deciphered | ImmunologyLabRoots
2022. 06. 01
Congratulations!! Our lab was awarded "Basic Science Research Program" grant funding!
National Research Foundation of Korea will support our research titled "Discovery of new bioactive natural products from Streptomyces sp. SNM55 producing novel cyclic depsipeptides" .
2022. 05. 19
Congratulations!! Our lab has been highlighted in Gachon News!
Our lab published a paper about Lyme disease in Journal of American Chemical Society (IF: 15.336) and has been selected as Gachon News on May 2022.
2022. 03. 01
We are new member of Gachon University!!
Our lab opend at College of Pharmacy, Gachon University, Incheon, Republic of Korea.
Let's join us!
